Dysregulated expression of TXNIP/TBP-2/VDUP1 in Corona virus 2019 (Covid-19) infected human cells.

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Thioredoxin interacting protein (TXNIP) is also known as Thioredoxin binding protein-2 (TBP-2) and vitamin D3 upregulated protein 1 (VDUP1). Scientists in Germany found that TXNIP/TBP-2/VDUP1 expression is dysregulated in Corona virus 2019 (covid-19) inflected human cells. TXNIP is known as the central regulator of aging process in humans and other species. TXNIP is the most critical determinant of diabetes and diabetes related complications. TXNIP is also an important regulator of cardiovascular diseases. TXNIP is a well known tumor suppresor for many human cancers. TXNIP plays important roles in carcinogenesis, cancer progression, hypoxia and malignancies. TXNIP plays important roles in the blood clotting process. TXNIP. Mitochondrial translocation of TXNIP works as the most critical signal for elevated ROS generation, mitochondrial damage, inflammasome activation and for initiation of inflammatory processes. TXNIP plays important roles in the T cell biology including T cell activation, T cell exhaustion and T cell death. TXNIP/TBP-2/VDUP1 may fit in the role to linked up all the pathologies related with the responses after the infection with corona virus-2019 or covid-19. The image used in the cover of the video was not made by myself. The image was collected from the online resources and was used without any prior permission.I would like to be sorry for that. The credit goes to the person who made such a beautiful image.
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