Pandemic update and risk to children

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Pascal Soriot

Trials will show vaccine efficacy equal to Pfizer-BioNTech at 95% and Moderna at 94.5%.

We think we have figured out the winning formula and how to get efficacy that, after two doses, is up there with everybody else

US

Flying over Christmas, 8,000,000

US COVID units

No family visitors

California

https://www.cdph.ca.gov/Programs/OPA/Pages/NR20-349.aspx

Cases, + 30,375 (Friday 25th) = 2,072,665

Seven - day positivity rate, 11.3%

As case numbers continue to rise in California, the total number of individuals who will have serious outcomes will also increase.

Deaths, 23,983

State wide ICU beds, zero

Gavin Newsom

Hospital numbers will double in the next 30 days

LA county

Hospitalizations tripled in past month

One COVID death every 10 minutes

Testing has begun for 2020 12 N501Y strain

https://covid19.ca.gov/equity/

Case rate for Pacific islanders, 20% higher than statewide

Latino death rate 23% higher

Black death rate 20% higher

Case rate, income areas less than $40,000, 7% higher

Multisystem Inflammatory Syndrome in Children (MIS-C)

As of December 21, 157 cases of MIS-C statewide

Counties with 11 cases or more

A rare inflammatory condition

Associated with COVID-19

Can damage multiple organ systems

Requires hospitalization

Can be life threatening

Index of suspicion

Fever that does not go away

Abdominal pain

Vomiting

Diarrhoea

Neck pain

Rash

Bloodshot eyes

Feeling tired

Contact your child's doctor immediately if your child has these symptoms.

Early diagnosis and treatment of patients is critical to preventing long-term complications.

2020 12 Variant

Denmark, 33

Germany, 1 (from UK)

Singapore, 1 (from UK)

France, 1 asymptomatic (from UK)

Japan, 5 (all from UK)

Spain, Australia, Lebanon, Sweden, Netherlands, Italy

Canada

Ontario

A couple from Durham Region

No known travel history or high-risk contacts

US testing

Genomic testing limited

https://www.washingtonpost.com/investigations/cdc-covid/2020/12/25/c2b418ae-4206-11eb-8db8-395dedaaa036_story.html

January 12, China publishes genome

January 12, Thailand diagnoses a sick traveller from Wuhan

January 13, WHO published test recipe

January 13, Thailand deploys a new test

February 26, CDC testing started

Delay, 46 days

US, CDC

Fifteen acre campus in Atlanta

Maintains offices and a staff of 170 epidemiologists, laboratory specialists in Thailand

CDC's budget, fiscal year 2018, $11.9 billion

Vaccination

Injections versus infections

https://coronavirus.data.gov.uk/details/cases

Grand European Kick Off, Today, Sunday 27th December

Population 446 million, 27 states

BioNTech-Pfizer vaccine only

https://twitter.com/vonderleyen/status/1342751465274806273?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1342751465274806273%7Ctwgr%5E%7Ctwcon%5Es1_&ref_url=https%3A%2F%2Fwww.dw.com%2Fen%2Fgermany-distributes-covid-19-vaccine-to-states-ahead-of-rollout%2Fa-56061628

Ursula von der Leyen
@vonderleyen
#EUvaccinationdays are a touching moment of unity. Vaccination is the lasting way out of the pandemic.

Saturday, 26th Pfizer, Germany, Slovakia, Hungary make a start

Other 25 countries today

Also UK, Serbia, Switzerland, Bahrain, Israel, Canada, United States

Germany

Population, 83 million

Received 160,000 doses

End of January, 700,000 doses per week

Pfizer vials, 5 to 7 doses

AZ working with Russia on vaccine development

Oxford

MHRA, Medicines and Healthcare Products Regulatory Agency

Mass rollout starts 4th January

One million people per week

Mass lateral flow antigen testing
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